CHOLESTERYL ESTER METABOLISM IN ATHEROMAS Hough and Zilversmit
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Effect of 17 beta estradiol on aortic cholesterol content and metabolism in cholesterol-fed rabbits.
Administration of estrogen to cholesterol-fed rabbits dramatically retarded arterial lesion development despite its lack of effect on plasma cholesterol concentration and on lipoprotein patterns. Cholesteryl ester influx into the aortic wall was also much lower in the estrogen-treated animals and paralleled the aortic cholesterol content in treated and untreated animals; the fraction of aortic ...
متن کاملPurification and characterization of lipid transfer protein(s) from human lipoprotein-deficient plasma.
Lipid transfer activities from human plasma have been characterized to determine whether triglyceride and cholesteryl ester transfer proteins are identical. After sequential purification by phenyl-Sepharose, CM-cellulose, chromatofocusing, and gel filtration, both triglyceride and cholesteryl ester transfer activities were purified approximately 15,000-fold compared to lipoprotein-deficient pla...
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